Regenerative aesthetics is a burgeoning field for skin rejuvenation and skin health restoration. Exosomes, or extracellular vesicles, represent a new and minimally invasive addition to the regenerative aesthetic toolbox. These nano-sized vesicles contain bioactive cargo with crucial roles in intercellular communication. Exosome technology, while still in its infancy, is now leveraged in regenerative aesthetic medicine due to its multifaceted role in targeting root causes of skin aging and improving overall tissue homeostasis. 

Different from stem cells, exosomes are nanoparticles that are pinched off from cells in the shape of a vesicle.  Inside each vesicle are rich sources of protein, DNA, and RNA from the originating cells. These vesicles can be taken up by other distant cells and affect the function of these target cells. Although exosomes are secreted by all cell types, those that are derived from stem cells (undefined cells that can develop into any cell type) have a powerful role in regenerative medicine by facilitating healing and repair processes.

Exosome therapy entails the medical use of exosomes for drug delivery, as well as regenerative or restorative measures to treat conditions such as tissue injury, osteoarthritis, chronic inflammation, fibromyalgia, degenerative diseases, and even cancer. Given their regenerative capabilities, exosomes are also used in medical aesthetics. Two areas of aesthetics where research has revealed the utility of exosome therapy are facial aesthetics and hair restoration.

There are commercially available exosome products derived from mesenchymal stem cells, plant-based stem cells, or adipose tissue stem cells. Doctors can use these stem cell–derived exosomes for skin reconstruction. Exosomes can be used to significantly increase skin collagen and elastin. This can result in changing the appearance of scars, decrease skin irritation, help with acne, address sagging skin, and reduce age spots and wrinkles. One way exosomes can be used in a facial procedure is by micro needling with exosomes. Exosomes are diffused over outer skin layers releasing growth factors to injured skin, thereby activating an enhanced wound healing process and tissue remodeling.

In addition to skin improvement applications, studies have shown that exosomes can successfully be used in the hair restoration arena. Unlike other common treatments for alopecia (hair loss), exosome therapy(Regenerative Medicine) promotes hair growth without reports of adverse effects. Exosomes injected into the scalp arrive at dermal papillae, located at the bottom of hair follicles, to help regrow hair.

Exosomes have versatile applications in many areas of medical therapeutics, and their successful and minimally invasive applications for medical aesthetics continue to expand as more is discovered about these powerful biologics.

Exosomes can be added to most facial treatments that cause micro-injury to the skin in order to deliver the exosomes to the deep dermis where they work best. Exosomes can be added after a hydra dermabrasion facial, chemical peel or micro-needling procedure performed at Solis Health and Beauty.

Disclaimer: The use of exosomes for cosmetic or regenerative medicine purposes is not FDA-approved. Exosome complexes are not drugs. They are not intended to prevent, treat, or cure diseases or medical conditions. They are not intended to be injected or delivered intravenously.

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